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葡萄糖转运/血糖通道荧光探针2-NBDG CAS 186689-07-6-AAT Bioquest荧光染料

发表于由

上海金畔生物科技有限公司代理AAT Bioquest荧光染料全线产品，欢迎访问AAT Bioquest荧光染料官网了解更多信息。
葡萄糖转运/血糖通道荧光探针2-NBDG CAS 186689-07-6葡萄糖转运/血糖通道荧光探针2-NBDG CAS 186689-07-6价格 2111
产品规格

5 mg

产品货号

产品参数
Ex (nm) 467 Em (nm) 538
分子量 342.26 溶剂 DMSO
存储条件 在零下15度以下保存, 避免光照
产品概述

产品基本信息

产品名称：葡萄糖转运/血糖通道荧光探针2-NBDG

CAS：186689-07-6

储存条件：-15℃避光防潮

保质期：12个月

 

产品物理化学光谱特性

分子量：342.26

外观：红色固体

溶剂：DMSO

激发波长（nm）：485

发射波长（nm）：540

 

产品介绍

葡萄糖转运/血糖通道荧光探针2-NBDG是美国AAT Bioquest生产的用于检测葡萄糖/血糖的荧光探针。2-NBDG是荧光标记的脱氧葡萄糖类似物，主要用于直接监测活细胞和组织对葡萄糖的摄取。它还用作检测瘤形成的局部造影剂。2-NBDG可用于实时共聚焦，高分辨率或宽视场荧光显微镜以及流式细胞术。可以通过氩激光在488nm激发探针以产生对环境敏感的荧光。它的光稳定性低于罗丹明荧光探针。金畔生物是AAT Bioquest的中国代理商，为您提供优质的葡萄糖转运/血糖通道荧光探针2-NBDG。 

点击查看光谱

 

参考文献

NT1014, a novel biguanide, inhibits ovarian cancer growth in vitro and in vivo
Authors: Lu Zhang, Jianjun Han, Amanda L Jackson, Leslie N Clark, Joshua Kilgore, Hui Guo, Nick Livingston, Kenneth Batchelor, Yajie Yin, Timothy P Gilliam
Journal: Journal of Hematology & Oncology (2016): 91

Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway
Authors: Lingqin Yuan, Xiugui Sheng, Adam K Willson, Dario R Roque, Jessica E Stine, Hui Guo, Hannah M Jones, Chunxiao Zhou, Victoria L Bae-Jump
Journal: Endocrine-related cancer (2015): 577–591

 

相关产品

产品名称 货号
2-NBDG 葡萄糖摄取检测试剂盒 Cat#23500

BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone B159

发表于由

BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone B159

  • 产品型号：  560842
  • 简单描述
  • BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone B159
    宿主物种：mouse
    反应物中：human
    规格：100T
    克隆号：B159
    应用：流逝
    现货供应中
详细介绍

BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone  B159

Brand：BD Pharmingen

Alternative Name：NCAM1; NCAM-1; Neural cell adhesion molecule 1; NCAM; NKH1; MSK39

Application：Flow cytometry (Routinely Tested) 

Immunogen：Human NK Cells

Storage Buffer：Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

 

BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone  B159

 

DESCRIPTION

 

The B159 monoclonal antibody specifically binds to CD56. CD56 is a heavily glycosylated adhesion protein that is present on a subpopulation of peripheral blood large granular lymphocytes that demonstrate natural killer activity. CD56 is also expressed on a subset of T cells but is not expressed on myeloid cells, erythrocytes or B cells. This antigen is a pan-NK-cell marker. CD56 is virtually identical to an isoform of the neural cell adhesion molecule (NCAM), a structure mediating homotypic and heterotypic cell-cell interactions.

 

 

 

 

 

 

FORMAT

BD PerCP-Cy5.5 Mouse Anti-Human CD56抗体Clone B159

Format

PerCP-Cy™5.5

Excitation Source

Blue 488 nm

Excitation Max

482 nm

Emission Max

695 nm

PerCP-Cy™5.5 is a tandem conjugate that combines PerCP with a cyanine dye. PerCP-Cy5.5 is not subject to photobeaching like PerCP and can be used with stream-in-air flow cytometers. It has less Fc receptor–mediated nonspecific staining than PE-Cy5. Additionally, the PerCP-Cy5.5 tandem conjugate is not as susceptible to fixative or light instability compared to APC-Cy7 and PE-Cy7.

Other Formats →

  • APC
  • Alexa Fluor® 488
  • Alexa Fluor® 647
  • Alexa Fluor® 700
  • BB515
  • Biotin
  • FITC
  • NA/LE
  • PE
  • PE-CF594
  • PE-Cy™5
  • PE-Cy™7
  • Purified
  • V450

    SUGGESTED COMPANION PRODUCTS

    Cat No. Description Size  
    550795 PerCP-Cy™5.5 Mouse IgG1 κ Isotype Control RUO 0.1 mg  
    555899 Lysing Buffer RUO 100 mL  

    RESOURCES & TOOLS

    • Spectrum Viewer
    • Panel Designer
    • Download TDS

    PREPARATION AND STORAGE

    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with PerCP-Cy5.5 under optimum conditions, and unconjugated antibody and free PerCP-Cy5.5 were removed. Storage of PerCP-Cy5.5 conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity.

     

    BD基质胶MATRIGEL MATRIX 5ML

    发表于由

    BD基质胶MATRIGEL MATRIX 5ML

    • 产品型号：  356234
    • 简单描述
    • BD基质胶MATRIGEL MATRIX 5ML
      产地：BD*
      规格：5ml
      大量现货促销中
    详细介绍

    BD基质胶MATRIGEL MATRIX 5ML

    产品介绍：

    BD Matrigel 基底膜/基质胶形成的三维培养基质，可促进上皮细胞、肝细胞、Sertoli细胞、黑色素瘤细胞、血管内皮细胞、甲状腺细胞及毛囊细胞等的贴壁与分化。同时，Matrigel还能影响乳腺上皮细胞的蛋白表达，支持外周神经的新生和牛输卵管上皮细胞的分化。

    BD基质胶MATRIGEL MATRIX 5ML

    使用指南：培养细胞时，Matrigel可无需稀释直接包被，包被厚度可为0.5 mm（薄层）或1.0 mm(厚层）。Matrigel也可以在无血清培养基中稀释后用于包被培养器皿表面，根据细胞类型和应用目的确定相应Matrigel浓度。
    保存条件和效期：-20℃下冷冻保存，避免多次冻融。保质期详见产品说明。
    纤维粘连蛋白（FN）
    纤维粘连蛋白(FN)存在于间隙基质和血浆中，通过RGD序列介导细胞的粘附。FN的主要功能是在伤口愈合过程中促进细胞的迁移。有FN包被的细胞培养表面，对细胞的粘附，伸展和增殖有促进作用。FN也可以用作无血清培养基的添加物。
    标准型
    BD Matrigel是从富含胞外基质蛋白的EHS小鼠肿瘤中提取出基底膜基质，其主要成分有层粘连蛋白、Ⅳ型胶原、巢蛋白、硫酸肝素糖蛋白，还包含生长因子和基质金属蛋白酶等。在室温条件下，Matrigel聚合形成具有生物学活性的三维基质，模拟体内细胞基底膜的结构、组成、物理特性和功能，有利于体外细胞的培养和分化，可用于对细胞形态、生化功能、迁移、侵染和基因表达等的研究。
    BD Matrigel基底膜/基质胶形成的三维培养基质，可促进上皮细胞、肝细胞、Sertoli细胞、黑色素瘤细胞、血管内皮细胞、甲状腺细胞及毛囊细胞等的贴壁与分化。同时，Matrigel还能影响乳腺上皮细胞的蛋白表达，支持外周神经的新生和牛输卵管上皮细胞的分化。
    不同配方的BD Matrigel可以满足不同的实验要求。低生长因子（GFR）的Matrigel基底膜基质适用于对基质成分要求严格的实验，如细胞信号通路和细胞因子的研究等。不含酚红的Matrigel适用于荧光检测或显色反应等分析。高浓度的Matrigel适用于研究血管生成、肿瘤细胞迁移和体内肿瘤模型的建立等。

    其他相关产品信息：

    BD Matrigel基底膜基质
    BD Matrigel TM Basement Membrane matrix     TM

    5 ml

    标准型

    356234

     

    10 ml

     

    354234

     

    5×10 ml

     

    356235

     

    10 ml

    高浓度(HC)

    354248

    BD Matrigel基底膜基质，无酚红
    BD Matrigel TM Matrix Phenol Red-free     TM

    10 ml

    标准型

    356237

     

    10 ml

    高浓度(HC)

    354262

    BD Matrigel基底膜基质，低生长因子
    Growth factor reduced (GFR) Matrigel matrix     TM

    5 ml

    标准型

    356230

     

    10 ml

    标准型

    354230

     

    10 ml

    高浓度(HC)

    354263

    BD Matrigel基底膜基质，GFR，无酚红 TM

    10 ml

    标准型

    356231

    来源：EHS小鼠肿瘤
    使用指南：培养细胞时， Matrigel 保存条件和效期：-20℃下冷冻保存，避免多次冻融。保质期详见产品说明。可无需稀释直接包被，包被厚度可为0.5 mm(薄层)或1.0 mm(厚层)。Matrigel也可以在无血清培养基中稀释后用于包被培养器皿表面，根据细胞类型和应用目的确定相应Matrigel浓度。
     

    纤维粘连蛋白(FN)

    纤维粘连蛋白(FN)存在于间隙基质和血浆中，通过RGD序列介导细胞的粘附。FN的主要功能是在伤口愈合过程中促进细胞的迁移。有FN包被的细胞培养表面，对细胞的粘附，伸展和增殖有促进作用。FN也可以用作无血清培养基的添加物。

    产品描述

    数量

    货号

    BD TM 纤维粘连蛋白，人
    BD TM Fibronectin, human

    1 mg

    354008

     

    5 mg

    356008

    来源：人血浆
    分子量：440 kD
    使用指南：根据细胞类型不同，推荐工作浓度为1-5 μg/cm2生长面积或5 ug/ml培养添加剂。
    保存条件和效期：冻干粉2-8℃下保存或溶解后-20℃下保存，避免多次冻融。保质期详见产品包装。

    美国BD公司Purified Mouse anti-TAZ抗体Clone M2-616

    发表于由

    美国BD公司Purified Mouse anti-TAZ抗体Clone M2-616

    • 产品型号：  560235
    • 简单描述
    • 美国BD公司Purified Mouse anti-TAZ抗体Clone M2-616
      规格：0.1mg
      货号：560235
      库存：现货
    详细介绍

    美国BD公司Purified Mouse anti-TAZ抗体Clone M2-616

    美国BD公司Purified Mouse anti-TAZ抗体Clone M2-616

    规格

    0.1 mg

    货号

    560235

    目录价

    ¥ 5,543.00

    Brand

    BD Pharmingen™

    Alternative Name

    WWTR1

    Concentration

    0.5 mg/ml

    Isotype

    Mouse BALB/c IgG2b, κ

    Reactivity

    Human (QC Testing)  Mouse (Tested in Development) 

    Application

    Western blot (Routinely Tested) 
    Bioimaging (Tested During Development) 

    Immunogen

    Human TAZ Recombinant Protein

    Storage Buffer

    Aqueous buffered solution containing ≤0.09% sodium azide.

    详细说明：

     

    DESCRIPTION

     

    Taz is a 49-kDa transcriptional co-activator with a PDZ-binding motif and is regulated by binding with 14-3-3 proteins. It plays a key role in differentiation of mesenchymal stem cells into either osteoblasts or adipocytes via interactions with key transcription factors Runx2 and PPAR γ . More recently, Taz was found to be a component of an E3 ubiquitin ligase involved in ubiquitin-dependent substrate proteolysis by mediating its interaction with the F-box protein β -Trcp. Therefore, Taz has dual functions of regulating protein degradation and transcription.

     

     

     

     

     

    FORMAT

    Format

    Purified

    SUGGESTED COMPANION PRODUCTS

    Cat No. Description Size  
    611449 HeLa Cell Lysate RUO 500 µg

     
    554656 Stain Buffer (FBS) RUO 500 mL

     
    554655 Fixation Buffer RUO 100 mL

     
    554723 Perm/Wash Buffer RUO 100 mL

     
    554002 HRP Goat Anti-Mouse Ig RUO 1 mL

     

    RESOURCES & TOOLS

    • Download TDS

    PREPARATION AND STORAGE

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Store undiluted at 4°C.

    PRODUCT NOTICES

    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to www.bdbiosciences。。ｃｏｍ/pharmingen/protocols for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Triton is a trademark of the Dow Chemical Company.
    5. This antibody has been developed and certified for the bioimaging application. However, a routine bioimaging test is not performed on every lot. Researchers are encouraged to titrate the reagent for optimal performance.