santacruz GSK-3 Inhibitor X分子量: 398.2分子式: C18H12BrN3O3可溶性: Soluble in DMSO
详细介绍
santacruz GSK-3 Inhibitor X santacruz GSK-3 Inhibitor X详细产品信息:
GSK-3 Inhibitor X (CAS 740841-15-0)
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Synonym:
BIO-Acetoxime; 6-Bromoindirubin-3′-acetoxime, BIA
Application:
A selective GSK-3α/β inhibitor
CAS Number:
740841-15-0
Purity:
≥95%
Molecular Weight:
398.21
Molecular Formula:
C18H12BrN3O3
Refer to Certificate of Analysis for lot specific data (including water content).
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GSK-3 Inhibitor X
sc-221689
1 mg
$115
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Description
GSK-3 Inhibitor X is an acetoxime analog of BIO which acts as a selective GSK-3α/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). GSK-3 Inhibitor X induces Wnt signaling and inhibits CD8+ T cell effector differentiation.