ambr® crossflow 切向流过滤系统

  • 产品介绍
  • 公司简介

The High Throughput Solution for Parallel Screening

・ Study factors for manufacturability
・ Up to 16 automated, parallel trials
・ Lowest process volumes C 5 mL recirculation volume

ambr® crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in membrane processes. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.

A small scale, high throughput automated system enables greater number of molecule | buffer combinations and process control  conditions to be investigated. As a result early stage R&D productivity and efficiency will be improved significantly while costs per  experiment are reduced.

ambr® crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of ambr® CF filter cassettes with 10 cm² membrane area. Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means ambr® crossflow is capable of performing membrane screenings with up to 16 ambr® CF filters simultaneously.

Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

ambr® crossflow 切向流过滤系统

ambr® crossflow 4- to 16-channel module with system controller

Flexibility for Automated Processing

Expand your ambr® crossflow system and tailor it to your actual demand with 4, 8, 12 or 16 channels.

Each ambr® crossflow module consists of four independent crossflow channels, and up to 4 modules can be managed by one control station. This enables you to perform membrane screening with up to 16 ambr® CF filters and 32 diafiltration buffers.

Increase R&D Productivity

ambr® crossflow can be used as a ranking tool, to optimise, for example:

・ process conditions, e.g. TMP or flowrate
・ processing conditions, e.g. buffer type or volumes required
・ pH and | or conductivity values

ambr® crossflow Overview

ambr® crossflow 切向流过滤系统

Intuitive Control Software

Control Functions Process Sequences Data Acquisition

ambr® crossflow 切向流过滤系统

System control is fully automated therefore requires minimal manual intervention when in operation. The 21” touch screen control system displays all process information allowing for user-friendly operation, even when editing the process on the fly.
Recipe design is intuitive with drag-and-drop preprogrammed phases and is also flexible, allowing users to design their own phases and recipes from scratch. Each channel operates independently with individual control of process conditions, set points and control strategy. ambr® crossflow software can additionally be installed on user PCs to enable writing of process sequences at your desk, before transferring to the control system.
Data is automatically collected and stored within the experiment folder. Experiment data can be viewed on the control system, or on a user PC with the ambr® crossflow software installed. Alternatively, data can be exported as .csv files.

Smart Scalability

Crossflow Solutions from Early to Late Process Development

ambr® crossflow 切向流过滤系统

SARTOFLOW® Smart

SARTOFLOW® Advanced

Linear scale up from 50 cm² to as much as 0.14 m² on SARTOFLOW® Smart and from 0.1m² to 2.1 m² on SARTOFLOW® Advanced at lowest recirculation volumes. Two systems that offer a combination of full flexibility and outstanding crossflow filtration performance.

Learn more about SARTOFLOW Systems

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    赛多利斯集团成立于1870年,总部位于德国哥廷根,在全球已拥有5,000多名员工。赛多利斯集团是一家国际领先的实验室仪器、生物制药技术和设备的供应商,提供生物工艺过程、实验室产品与服务、工业称重产品。

     赛多利斯致力于为中国客户提供一流的实验室仪器如实验室天平、移液器和纯水设备、实验室耗材包括实验室过滤器和移液器吸头,以及优质的服务。其生物工艺解决方案涵盖过滤、液体处理、发酵、细胞培养和纯化,并致力于生物制药行业过程控制,为生物制药开发、质量控制和生产工艺提供前沿设备和完整解决方案。实验室产品及服务部主要生产实验室仪器及耗材。工业称重专注于对食品,化工和制药行业生产工艺过程中的称重、监控和控制。

     赛多利斯集团在欧洲、亚洲以及美洲都拥有自己的生产及研发机构,并已在全球110多个国家设立了办事处及代表处。2012年,赛多利斯集团取得了8.457亿欧元的销售额。   

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